Venous Thromboembolism and Bleeding Risk in a Population with Obesity Hospitalized for Surgery and Receiving Enoxaparin for Thromboprophylaxis - Takeaways - MDSpire

Venous Thromboembolism and Bleeding Risk in a Population with Obesity Hospitalized for Surgery and Receiving Enoxaparin for Thromboprophylaxis

  • By

  • Walter Ageno

  • Marc Carrier

  • Christine Stroh

  • Yasmina Djoudi

  • Mohamed Abdel-Moneim

  • Irfan Khan

  • Ekaterina Ponomareva

  • May 18, 2026

  • 0 min

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  • 1

    Obesity significantly increases the risk of venous thromboembolic events (VTE) in surgical patients, particularly within the first 30 days post-discharge.

  • 2

    Patients with obesity undergoing major surgery require pharmacological thromboprophylaxis, yet guidelines for this population remain insufficient.

  • 3

    The study analyzed the use of enoxaparin for thromboprophylaxis in hospitalized surgical patients with obesity, focusing on dosing and duration.

  • 4

    VTE risk factors and bleeding complications were assessed to guide optimal thromboprophylaxis regimens for obese surgical patients.

  • 5

    The research utilized data from the Optum Market Clarity database, encompassing a diverse cohort of surgical patients with obesity.

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