Nonlinear Association of Serum Sodium with Urine Output in Postoperative Pediatric Cardiac Patients Receiving Furosemide: A Retrospective Study - Takeaways - MDSpire

Nonlinear Association of Serum Sodium with Urine Output in Postoperative Pediatric Cardiac Patients Receiving Furosemide: A Retrospective Study

  • By

  • David Gilad

  • Arielle Jacover

  • Shalom Levy

  • Reut Kassif Lerner

  • Eitan Keizman

  • David Mishali

  • Yelena Skourikhin

  • Uriel Katz

  • Tal Tirosh Wagner

  • Itai M. Pessach

  • Evyatar Hubara

  • June 26, 2026

  • 0 min

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  • 1

    Furosemide is essential for managing postoperative fluid overload in pediatric cardiac surgery patients by promoting natriuresis and diuresis.

  • 2

    Fluid overload in pediatric cardiac surgery is linked to increased morbidity, longer ICU stays, and higher acute kidney injury risk.

  • 3

    The study analyzed the relationship between serum sodium levels and urine output in pediatric cardiac patients receiving furosemide.

  • 4

    Two hundred sixty-four pediatric patients were included, focusing on urine output and serum sodium during the early postoperative period.

  • 5

    The study utilized flexible statistical modeling to explore the nonlinear relationship between serum sodium and urine output.

Original Source(s)

Nonlinear Association of Serum Sodium with Urine Output in Postoperative Pediatric Cardiac Patients Receiving Furosemide: A Retrospective Study

  • by David Gilad, Arielle Jacover, Shalom Levy, Reut Kassif Lerner, Eitan Keizman, David Mishali, Yelena Skourikhin, Uriel Katz, Tal Tirosh Wagner, Itai M. Pessach, Evyatar Hubara

  • June 26, 2026

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