Neurological recovery after liver transplantation in a severely disabled adolescent with Wilson disease: a 1-year follow-up case report - Takeaways - MDSpire

Neurological recovery after liver transplantation in a severely disabled adolescent with Wilson disease: a 1-year follow-up case report

  • By

  • Konstantin Semash

  • Timur Dzhanbekov

  • Mansur Nasirov

  • Alla Syrkina

  • Bakhtiyarjon Umarov

  • June 17, 2026

  • 0 min

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  • 1

    A 15-year-old girl with severe neurological Wilson disease underwent liver transplantation due to rapid deterioration and hepatic decompensation.

  • 2

    The patient's total UWDRS score improved from 162 at presentation to 59 one year post-transplant, indicating significant neurological recovery.

  • 3

    Postoperative complications included aspiration pneumonia, requiring reintubation and prolonged enteral feeding during recovery.

  • 4

    Continuous neuropsychosocial rehabilitation was implemented throughout the patient's recovery process in various care settings.

  • 5

    This case suggests that severe neurological impairment should not be an absolute contraindication for liver transplantation in selected patients.

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