Atherogenic index of plasma predicts progression of diabetic kidney disease - Takeaways - MDSpire

Atherogenic index of plasma predicts progression of diabetic kidney disease

  • By

  • Hong-Mou Shih

  • Sung-Chen Liu

  • Kuo-Liong Chien

  • Hsien-Yu Fan

  • Ming-Chieh Tsai

  • Shih-Ming Chuang

  • June 5, 2026

  • 0 min

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  • 1

    The atherogenic index of plasma (AIP) is calculated as the logarithm of the triglyceride-to-HDL cholesterol ratio.

  • 2

    In a study of 936 adults with type 2 diabetes, higher AIP was linked to increased risks of albuminuria progression and eGFR decline.

  • 3

    Each standard deviation increase in AIP correlated with a 25% higher risk of albuminuria progression and a 59% higher risk of eGFR decline.

  • 4

    Participants in the highest AIP quartile faced over double the risk of albuminuria progression and more than triple the risk of eGFR decline.

  • 5

    The study suggests AIP may serve as a marker for assessing the risk of diabetic kidney disease progression in type 2 diabetes.

Original Source(s)

Atherogenic index of plasma predicts progression of diabetic kidney disease

  • by Hong-Mou Shih, Sung-Chen Liu, Kuo-Liong Chien, Hsien-Yu Fan, Ming-Chieh Tsai, Shih-Ming Chuang

  • June 5, 2026

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