Non-metastatic pediatric head and neck rhabdomyosarcoma: a 24-year retrospective experience from Jordan - Takeaways - MDSpire

Non-metastatic pediatric head and neck rhabdomyosarcoma: a 24-year retrospective experience from Jordan

  • By

  • Arwa Kiswani

  • Omar Jaber

  • Ahmad Kh. Ibrahimi

  • Nasim Sarhan

  • Yacoub A. Yousef

  • Mona Mohammad

  • Rula Al-Qawabah

  • Iyad Sultan

  • Hadeel Halalsheh

  • July 16, 2026

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  • 1

    The study analyzed 98 pediatric patients with non-metastatic head and neck rhabdomyosarcoma diagnosed between January 2001 and May 2025.

  • 2

    Among the patients, 79% had non-metastatic disease, with a median age at diagnosis of 5.9 years and a male-to-female ratio of 1:1.

  • 3

    The most common primary sites were the parameningeal region (40%) and the orbital region (26%), with 66% of tumors being embryonal.

  • 4

    The 5-year overall survival rate was 70.1%, with significant variability based on primary site, particularly lower rates for parameningeal tumors.

  • 5

    Local control strategies were emphasized, as 30% of patients experienced relapse, primarily due to local recurrence or progression.

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