Evaluation of eradication efficacy and optimization strategies for Helicobacter pylori infection based on real-world data: a multivariable retrospective study - Takeaways - MDSpire

Evaluation of eradication efficacy and optimization strategies for Helicobacter pylori infection based on real-world data: a multivariable retrospective study

  • By

  • Ziqi He

  • Linde He

  • Yaliu Qu

  • Yiting Zheng

  • Leyi Dou

  • Shijuan Luo

  • Zhenhao Ye

  • Chaoyuan Huang

  • July 1, 2026

  • 0 min

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  • 1

    The study evaluated eradication efficacy of H. pylori treatment regimens using real-world data from 897 patients between September 2022 and September 2025.

  • 2

    Quadruple therapy showed the highest eradication rates at 81.42% (ITT) and 93.76% (PP), outperforming dual and triple therapies.

  • 3

    Prescription appropriateness significantly influenced eradication success in the quadruple therapy group, with a p-value of less than 0.01.

  • 4

    Female patients had a higher eradication success rate in the quadruple therapy group, with an odds ratio of 2.53.

  • 5

    Older patients and those using traditional Chinese medicine demonstrated better follow-up compliance in the study.

Original Source(s)

Evaluation of eradication efficacy and optimization strategies for Helicobacter pylori infection based on real-world data: a multivariable retrospective study

  • by Ziqi He, Linde He, Yaliu Qu, Yiting Zheng, Leyi Dou, Shijuan Luo, Zhenhao Ye, Chaoyuan Huang

  • July 1, 2026

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