Rethinking No-Flow Duration in Older Adults With Out-of-Hospital Cardiac Arrest - Takeaways - MDSpire
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Reevaluating No-Flow Time in Elderly Patients Experiencing Out-of-Hospital Cardiac Arrest

  • By

  • Yohei Okada

  • September 1, 2026

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  • 1

    Out-of-hospital cardiac arrest (OHCA) increasingly affects older adults, who represent the majority of cases in developed countries.

  • 2

    Kishihara et al. assessed the impact of no-flow duration on neurological outcomes in older adults with witnessed cardiogenic OHCA.

  • 3

    The study found that the no-flow duration threshold for a favorable neurological outcome decreases with age, from 14 minutes for ages 65-74 to 0 minutes for those 95 and older.

  • 4

    The authors emphasize the need for caution in interpreting their findings due to variations in defining no-flow duration across studies.

  • 5

    Clinical application of the study's results should consider individual patient factors, as a 1% probability does not imply futility in resuscitation efforts.

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