68Ga-PSMA-PET screening and transponder-guided salvage radiotherapy to the prostate bed alone for biochemical recurrence following prostatectomy: interim outcomes of a phase II trial - Takeaways - MDSpire

68Ga-PSMA-PET screening and transponder-guided salvage radiotherapy to the prostate bed alone for biochemical recurrence following prostatectomy: interim outcomes of a phase II trial

  • By

  • Patrick Bowden

  • Andrew W. See

  • Kevin So

  • Nathan Lawrentschuk

  • Daniel Moon

  • Declan G. Murphy

  • Ranjit Rao

  • Alan Crosthwaite

  • Dennis King

  • Hodo Haxhimolla

  • Jeremy Grummet

  • Paul Ruljancich

  • Dennis Gyomber

  • Adam Landau

  • Nicholas Campbell

  • Mark Frydenberg

  • Lloyd M. L. Smyth

  • Skye Nolan

  • Stella M. Gwini

  • Dean P. McKenzie

  • June 2, 2021

  • 0 min

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  • 1

    One in three men with prostate cancer experiences recurrence within 10 years after radical prostatectomy, indicated by rising PSA levels.

  • 2

    68Ga-PSMA-PET imaging is more sensitive than conventional methods for detecting recurrent prostate cancer, influencing treatment strategies for many patients.

  • 3

    This study evaluates the outcomes of transponder-guided salvage radiotherapy to the prostate bed alone for patients with biochemical recurrence.

  • 4

    The primary endpoint is the rate of freedom from biochemical relapse following salvage radiotherapy, with secondary endpoints including toxicity and quality of life.

  • 5

    Patients with negative 68Ga-PSMA-PET results or positive findings limited to the prostate bed received targeted salvage radiotherapy without androgen deprivation therapy.

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