Development and validation of a predictive model for postoperative complications in elderly patients with locally advanced esophageal squamous cell carcinoma utilizing the POSSUM system and inflammatory markers - Takeaways - MDSpire

Development and validation of a predictive model for postoperative complications in elderly patients with locally advanced esophageal squamous cell carcinoma utilizing the POSSUM system and inflammatory markers

  • By

  • Ying Zhang

  • Haifang Zhu

  • Fujuan Yang

  • Lei Yang

  • January 27, 2026

  • 0 min

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  • 1

    Elderly patients with locally advanced esophageal squamous cell carcinoma face significant postoperative complications affecting recovery.

  • 2

    The POSSUM system is commonly used for surgical risk assessment but has limitations in predicting complications for elderly patients.

  • 3

    This study aims to enhance the POSSUM system by incorporating inflammatory markers to improve prediction accuracy for postoperative complications.

  • 4

    A total of 235 elderly patients were included in the study, focusing on those undergoing radical surgery for esophageal squamous cell carcinoma.

  • 5

    Postoperative complications were classified using the Clavien-Dindo Classification System, with common issues including pulmonary infection and anastomotic leakage.

Original Source(s)

Development and validation of a predictive model for postoperative complications in elderly patients with locally advanced esophageal squamous cell carcinoma utilizing the POSSUM system and inflammatory markers

  • by Ying Zhang, Haifang Zhu, Fujuan Yang, Lei Yang

  • January 27, 2026

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