Prognostic value of androgen receptor expression in ER-positive/HER2-negative breast cancer: evidence from a contemporary Chinese cohort

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This study analyzed 422 ER+/HER2− breast cancer patients from a Chinese cohort to evaluate the prognostic significance of androgen receptor expression.
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Higher androgen receptor expression was significantly associated with prolonged disease-free survival in the studied patient cohort.
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No significant association was found between androgen receptor expression and overall survival during the follow-up period.
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In patients receiving neoadjuvant chemotherapy without pathological complete response, higher androgen receptor expression correlated with better disease-free survival.
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The findings suggest that androgen receptor expression may have prognostic value in ER+/HER2− breast cancer, warranting further prospective studies.

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