Safety and feasibility of combined transanal total mesorectal excision with delayed coloanal anastomosis in high-risk patients with low rectal cancer - Takeaways - MDSpire
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Evaluating the Safety and Practicality of Combined Transanal Total Mesorectal Excision and Delayed Coloanal Anastomosis in High-Risk Low Rectal Cancer Patients

  • By

  • Y. Yue

  • Y. Sun

  • Y. Huang

  • L. Xue

  • T. Wang

  • G. Luo

  • April 6, 2026

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  • 1

    Transanal total mesorectal excision (taTME) improves tumor localization but is associated with higher anastomotic leakage rates compared to traditional laparoscopic methods.

  • 2

    Delayed coloanal anastomosis (DCAA) may reduce anastomotic leakage risk by allowing tissue repair and avoiding diverting stomas in high-risk low rectal cancer patients.

  • 3

    The study included 74 high-risk low rectal cancer patients, comparing outcomes of DCAA-taTME and immediate coloanal anastomosis with diverting ileostomy.

  • 4

    High-risk factors for patients included obesity, diabetes, and previous neoadjuvant therapy, which complicate surgical outcomes in low rectal cancer.

  • 5

    This research aims to provide contemporary evidence on the safety and feasibility of DCAA-taTME in reducing complications without compromising functional results.

Original Source(s)

Safety and feasibility of combined transanal total mesorectal excision with delayed coloanal anastomosis in high-risk patients with low rectal cancer

  • by Y. Yue, Y. Sun, Y. Huang, L. Xue, T. Wang, G. Luo

  • April 6, 2026

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