Safety and feasibility of combined transanal total mesorectal excision with delayed coloanal anastomosis in high-risk patients with low rectal cancer

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Transanal total mesorectal excision (taTME) improves tumor localization but is associated with higher anastomotic leakage rates compared to traditional laparoscopic methods.
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Delayed coloanal anastomosis (DCAA) may reduce anastomotic leakage risk by allowing tissue repair and avoiding diverting stomas in high-risk low rectal cancer patients.
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The study included 74 high-risk low rectal cancer patients, comparing outcomes of DCAA-taTME and immediate coloanal anastomosis with diverting ileostomy.
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High-risk factors for patients included obesity, diabetes, and previous neoadjuvant therapy, which complicate surgical outcomes in low rectal cancer.
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This research aims to provide contemporary evidence on the safety and feasibility of DCAA-taTME in reducing complications without compromising functional results.

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