Comparative Effectiveness of Conventional Treatment and Acoustic Therapy for Acute Tinnitus in Patients with Idiopathic Sudden Sensorineural Hearing Loss: A Randomized Controlled Study - Takeaways - MDSpire

Comparative Effectiveness of Conventional Treatment and Acoustic Therapy for Acute Tinnitus in Patients with Idiopathic Sudden Sensorineural Hearing Loss: A Randomized Controlled Study

  • By

  • Xinyi Wang

  • Ke Qiu

  • Yuyang Zhang

  • Sen Yang

  • Yanhong Xu

  • Xiaosong Mu

  • Yaxin Luo

  • Wendu Pang

  • Jiangnan Han

  • Chunhong Hu

  • Jia Chen

  • Ning Ma

  • Wen He

  • Wei Dai

  • Yang Zou

  • Lingfeng Xiong

  • Hongchang Chen

  • Weifeng Chen

  • Dengyun Zhang

  • Guanghui Zhang

  • Zhen Hu

  • Lintong Dai

  • Xiaohai Liu

  • Bingcai He

  • Xiaobing Pu

  • Wei Xu

  • Jianjun Ren

  • Yu Zhao

  • November 28, 2025

  • 0 min

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  • 1

    Idiopathic sudden sensorineural hearing loss (ISSHL) affects 10–27 cases per 100,000 people annually, often accompanied by distressing tinnitus.

  • 2

    Current ISSHL management primarily involves systemic steroids, which show limited efficacy in alleviating acute tinnitus.

  • 3

    Personalized acoustic therapy (AT) offers a novel approach to managing ISSHL-related tinnitus, integrating peripheral and central modulation techniques.

  • 4

    A multi-center randomized controlled trial is assessing the effectiveness of standard care with and without personalized AT for ISSHL-related tinnitus.

  • 5

    The trial involves 19 clinical centers and aims to provide evidence for improving treatment outcomes in patients with ISSHL and concurrent tinnitus.

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