Comparative Effectiveness of Conventional Treatment and Acoustic Therapy for Acute Tinnitus in Patients with Idiopathic Sudden Sensorineural Hearing Loss: A Randomized Controlled Study - Takeaways - MDSpire
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Comparative Effectiveness of Conventional Treatment and Acoustic Therapy for Acute Tinnitus in Patients with Idiopathic Sudden Sensorineural Hearing Loss: A Randomized Controlled Study

  • By

  • Xinyi Wang

  • Ke Qiu

  • Yuyang Zhang

  • Sen Yang

  • Yanhong Xu

  • Xiaosong Mu

  • Yaxin Luo

  • Wendu Pang

  • Jiangnan Han

  • Chunhong Hu

  • Jia Chen

  • Ning Ma

  • Wen He

  • Wei Dai

  • Yang Zou

  • Lingfeng Xiong

  • Hongchang Chen

  • Weifeng Chen

  • Dengyun Zhang

  • Guanghui Zhang

  • Zhen Hu

  • Lintong Dai

  • Xiaohai Liu

  • Bingcai He

  • Xiaobing Pu

  • Wei Xu

  • Jianjun Ren

  • Yu Zhao

  • November 28, 2025

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  • 1

    Idiopathic sudden sensorineural hearing loss (ISSHL) affects 10–27 cases per 100,000 people annually, often accompanied by distressing tinnitus.

  • 2

    Current ISSHL management primarily involves systemic steroids, which show limited efficacy in alleviating acute tinnitus.

  • 3

    Personalized acoustic therapy (AT) offers a novel approach to managing ISSHL-related tinnitus, integrating peripheral and central modulation techniques.

  • 4

    A multi-center randomized controlled trial is assessing the effectiveness of standard care with and without personalized AT for ISSHL-related tinnitus.

  • 5

    The trial involves 19 clinical centers and aims to provide evidence for improving treatment outcomes in patients with ISSHL and concurrent tinnitus.

Original Source(s)

Comparative Effectiveness of Conventional Treatment and Acoustic Therapy for Acute Tinnitus in Patients with Idiopathic Sudden Sensorineural Hearing Loss: A Randomized Controlled Study

  • by Xinyi Wang, Ke Qiu, Yuyang Zhang, Sen Yang, Yanhong Xu, Xiaosong Mu, Yaxin Luo, Wendu Pang, Jiangnan Han, Chunhong Hu, Jia Chen, Ning Ma, Wen He, Wei Dai, Yang Zou, Lingfeng Xiong, Hongchang Chen, Weifeng Chen, Dengyun Zhang, Guanghui Zhang, Zhen Hu, Lintong Dai, Xiaohai Liu, Bingcai He, Xiaobing Pu, Wei Xu, Jianjun Ren, Yu Zhao

  • November 28, 2025

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