Comparative performance of mitral E/e’ versus inferior vena cava variability for predicting fluid responsiveness in mechanically ventilated adults with shock

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Fluid resuscitation is crucial in shock management, requiring accurate prediction of fluid responsiveness to avoid adverse outcomes.
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The inferior vena cava variability index (IVCVI) is validated for assessing fluid responsiveness in mechanically ventilated patients.
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Mitral E/e’ ratio, while useful for evaluating left ventricular diastolic function, showed moderate discrimination for fluid responsiveness.
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In the study, IVCVI demonstrated superior performance over mitral E/e’ in predicting fluid responsiveness among shock patients.
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Operational thresholds for IVCVI and mitral E/e’ were established, aiding in the identification of likely fluid responders.

Critical Care

by Surat Tongyoo, Chailat Maluangnon, Anutr Thitayanapong, Suttisak Wattanasansomboon, Katsakron Kheawkaew
July 1, 2026

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