Clinical challenges and therapeutic strategies in women with endometriosis, deep infiltrating endometriosis, and/or adenomyosis undergoing assisted reproductive technologies: a narrative review - Takeaways - MDSpire
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Therapeutic Approaches and Clinical Obstacles in Women with Endometriosis, Deep Infiltrating Endometriosis, and Adenomyosis Undergoing Assisted Reproductive Technologies: A Narrative Review

  • By

  • Cemil Kaya

  • May 18, 2026

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  • 1

    Endometriosis and adenomyosis are significant causes of infertility, often coexisting and impacting reproductive outcomes.

  • 2

    Deep infiltrating endometriosis (DIE) is a severe form associated with adenomyosis, leading to reduced oocyte yield and embryo quality.

  • 3

    IVF/ICSI outcomes are controversial in adenomyosis, with studies indicating negative effects, especially in diffuse adenomyosis.

  • 4

    Cumulative live birth rates provide a better reflection of ART outcomes in patients with endometriosis and adenomyosis.

  • 5

    Pre-ART screening using ultrasonography and MRI is recommended due to increased pregnancy complications associated with these conditions.

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