Case Report: Persistent fetal vasculature associated with lenticular coloboma - Takeaways - MDSpire

Case Report: Persistent fetal vasculature associated with lenticular coloboma

  • By

  • Naiyu Sun

  • Jinchang Tian

  • Hong Zhang

  • July 10, 2026

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  • 1

    Persistent fetal vasculature (PFV) is a rare congenital ocular anomaly characterized by fibrovascular stalks in the vitreous cavity.

  • 2

    This case report presents a 23-year-old female with PFV co-occurring with lenticular coloboma, a rare combination.

  • 3

    The patient exhibited poor vision, with a localized central posterior subcapsular opacity and elongated ciliary processes detected.

  • 4

    Anterior segment optical coherence tomography (AS-OCT) was crucial in diagnosing anterior PFV and visualizing associated defects.

  • 5

    The patient underwent optimized surgery, including cataract extraction and anterior vitrectomy, with successful intraocular lens implantation.

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