The triglyceride-glucose–waist-to-height ratio is the strongest predictor of reduced kidney function in elderly hypertensive patients - Takeaways - MDSpire

The triglyceride-glucose–waist-to-height ratio is the strongest predictor of reduced kidney function in elderly hypertensive patients

  • By

  • Jiaying Ling

  • Shu Xie

  • Yanyan Zhang

  • Danxiang Chen

  • Changwei Lü

  • Gongcheng Wang

  • Xueqin Li

  • June 15, 2026

  • 0 min

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  • 1

    The study identifies the triglyceride-glucose-waist-to-height ratio (TyG-WHtR) as a significant predictor of reduced kidney function in elderly hypertensive patients.

  • 2

    Elevated TyG-WHtR correlates negatively with high-density lipoprotein cholesterol and positively with measures of adiposity and fasting plasma glucose.

  • 3

    In a cohort of 3,764 hypertensive adults aged 65 and older, 16.25% exhibited reduced estimated glomerular filtration rate (eGFR).

  • 4

    TyG-WHtR demonstrated improved predictive ability for impaired renal function after adjustment, with an AUC of 0.864.

  • 5

    The findings suggest that TyG-WHtR may serve as an effective marker for early identification of renal dysfunction in older hypertensive patients.

Original Source(s)

The triglyceride-glucose–waist-to-height ratio is the strongest predictor of reduced kidney function in elderly hypertensive patients

  • by Jiaying Ling, Shu Xie, Yanyan Zhang, Danxiang Chen, Changwei Lü, Gongcheng Wang, Xueqin Li

  • June 15, 2026

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