Cutaneous SCC Trends Across Sex and Age - Takeaways - MDSpire

Cutaneous SCC Trends Across Sex and Age

  • By

  • Kathryn Wighton

  • February 2, 2026

  • 3 min

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  • 1

    The study analyzed 109,787 cases of cutaneous squamous cell carcinoma (cSCC) and carcinoma in situ from Denmark between 2005 and 2023.

  • 2

    Incidence rates for cSCC reached 131.6 per 100,000 person-years in males and 77.7 in females, with annual increases of 2.6% and 3.1%, respectively.

  • 3

    Carcinoma in situ showed a significant rise, particularly after 2018, with incidence rates of 89.4 in males and 78.6 in females.

  • 4

    Keratoacanthoma incidence declined over the study period, with rates around 28 per 100,000 person-years for both sexes.

  • 5

    The study highlighted age-specific trends, showing higher incidence rates in females aged 40 to 59 years for all keratinocyte neoplasms.

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