Beyond the Auditory: Anxiety Bridges Sleep Disturbances and Depressive Symptoms to Tinnitus Handicap - Takeaways - MDSpire

Beyond the Auditory: Anxiety Bridges Sleep Disturbances and Depressive Symptoms to Tinnitus Handicap

  • By

  • Fan, Lijuan

  • Fan, LiTing

  • Wu, Qiqi

  • Zhou, Jie

  • Wu, Liya

  • Hu, Hantong

  • Gao, Hong

  • May 11, 2026

  • 0 min

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  • 1

    Tinnitus severity correlates positively with anxiety, depression, and sleep disturbances, indicating a complex interplay among these factors.

  • 2

    Multivariate regression analysis identified age, sleep quality, and anxiety as independent predictors of increased tinnitus handicap.

  • 3

    Anxiety partially mediates the relationship between sleep disturbances and tinnitus severity, with a mediation effect of 31.7%.

  • 4

    Anxiety fully mediates the relationship between depressive symptoms and tinnitus severity, highlighting its central role.

  • 5

    The mediating effect of anxiety is more pronounced in middle-aged and elderly individuals, females, and those with left-sided tinnitus.

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