Association between impaired peripheral thyroid hormone sensitivity and coronary heart disease in type 2 diabetes: the potential mediating role of albumin - Takeaways - MDSpire

Association between impaired peripheral thyroid hormone sensitivity and coronary heart disease in type 2 diabetes: the potential mediating role of albumin

  • By

  • Binghua Xue

  • Yalei Liu

  • Jingyi Wan

  • Shasha Tang

  • Xiaoyang Shi

  • Jin Cao

  • Huijuan Yuan

  • June 17, 2026

  • 0 min

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  • 1

    Type 2 diabetes mellitus significantly increases the risk of cardiovascular mortality, particularly from coronary heart disease.

  • 2

    Impaired peripheral thyroid hormone sensitivity is positively associated with coronary heart disease in patients with type 2 diabetes.

  • 3

    The free triiodothyronine to free thyroxine ratio serves as a useful indicator for assessing coronary heart disease risk.

  • 4

    Serum albumin levels are inversely related to coronary heart disease risk and may mediate the relationship with thyroid hormone sensitivity.

  • 5

    The study highlights the importance of evaluating thyroid hormone sensitivity and albumin levels in managing cardiovascular risk in diabetes.

Original Source(s)

Association between impaired peripheral thyroid hormone sensitivity and coronary heart disease in type 2 diabetes: the potential mediating role of albumin

  • by Binghua Xue, Yalei Liu, Jingyi Wan, Shasha Tang, Xiaoyang Shi, Jin Cao, Huijuan Yuan

  • June 17, 2026

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