Extent of the low-density line is associated with time to fracture in children with congenital anterolateral bowing of the tibia: a retrospective survival analysis - Takeaways - MDSpire

Extent of the low-density line is associated with time to fracture in children with congenital anterolateral bowing of the tibia: a retrospective survival analysis

  • By

  • Jiaqi Tian

  • Ge Yang

  • Yonghong Xie

  • Le Xu

  • Lan Yin

  • Yaqi Ouyang

  • Yinzhi Yi

  • Jianhui Xie

  • June 15, 2026

  • 0 min

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  • 1

    Congenital anterolateral bowing of the tibia (ALBT) is a precursor to congenital pseudarthrosis of the tibia, marked by a low-density line (LDL) on radiographs.

  • 2

    In a study of 40 children with ALBT, 77.5% experienced fractures, with 61.3% occurring within 6 months of LDL detection.

  • 3

    Kaplan–Meier analysis revealed significant differences in fracture-free survival based on LDL proportion, with shorter times to fracture in higher LDL groups.

  • 4

    Larger LDL proportions correlated with increased fracture risk, particularly in the 1/3–2/3 and >2/3 groups compared to the <1/3 group.

  • 5

    The findings suggest LDL may serve as an imaging marker for fracture timing, indicating a need for closer monitoring within 6 months of LDL detection.

Original Source(s)

Extent of the low-density line is associated with time to fracture in children with congenital anterolateral bowing of the tibia: a retrospective survival analysis

  • by Jiaqi Tian, Ge Yang, Yonghong Xie, Le Xu, Lan Yin, Yaqi Ouyang, Yinzhi Yi, Jianhui Xie

  • June 15, 2026

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