Leukoencephalopathy following stereotactic radiosurgery for breast cancer brain metastases: a single-center analysis of 1,077 lesions - Takeaways - MDSpire

Leukoencephalopathy following stereotactic radiosurgery for breast cancer brain metastases: a single-center analysis of 1,077 lesions

  • By

  • Salem M. Tos

  • Bardia Hajikarimloo

  • Georgios Mantziaris

  • Mariam Ishaque

  • Purushotham Ramanathan

  • David Schlesinger

  • Jason P. Sheehan

  • March 14, 2025

  • 0 min

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  • 1

    Breast cancer frequently metastasizes to the brain, with 7% to 16% of patients presenting with brain metastases at diagnosis.

  • 2

    Stereotactic radiosurgery (SRS) is an advanced treatment option that delivers high doses of radiation to brain metastases, improving outcomes.

  • 3

    Leukoencephalopathy is a significant delayed adverse effect of radiation therapy, impacting cognitive functions and associated with vascular damage.

  • 4

    This study analyzed 1,077 lesions from 125 patients to evaluate clinical and radiological outcomes of leukoencephalopathy post-SRS.

  • 5

    The research adhered to ethical guidelines and utilized comprehensive data collection, including patient demographics and treatment parameters.

Original Source(s)

Leukoencephalopathy following stereotactic radiosurgery for breast cancer brain metastases: a single-center analysis of 1,077 lesions

  • by Salem M. Tos, Bardia Hajikarimloo, Georgios Mantziaris, Mariam Ishaque, Purushotham Ramanathan, David Schlesinger, Jason P. Sheehan

  • March 14, 2025

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