The Changing Landscape of Maintenance Therapy in Newly Diagnosed Multiple Myeloma: A Systematic Review With Network Meta-Analysis of the European Myeloma Network (EMN) - Takeaways - MDSpire
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Evolving Approaches to Maintenance Therapy in Newly Diagnosed Multiple Myeloma: A Systematic Review and Network Meta-Analysis from the European Myeloma Network (EMN)

  • By

  • Heinz Ludwig

  • Evangelos Terpos

  • Francesca Gay

  • Niels W. C. J. van de Donk

  • Sarah Bernhard

  • Monika Engelhardt

  • Gordon Cook

  • Fredrik Schjesvold

  • Hermann Einsele

  • Graham Jackson

  • Charlotte Pawlyn

  • María-Victoria Mateos

  • Sonja Zweegman

  • Martin Schreder

  • Meral Beksaç

  • Christoph Driessen

  • Enrique M. Ocio

  • Rakesh Popat

  • Leo Rasche

  • Cyrille Touzeau

  • Pellegrino Musto

  • Annemiek Broijl

  • Meletios Dimopoulos

  • Roman Hajek

  • Mario Boccadoro

  • Pieter Sonneveld

  • June 18, 2026

Share

  • 1

    Maintenance therapy is essential in managing newly diagnosed multiple myeloma, focusing on sustaining therapeutic benefits with minimal toxicity.

  • 2

    Lenalidomide maintenance after autologous stem-cell transplantation is established as the standard of care, improving progression-free survival and overall survival.

  • 3

    Continuous treatment for patients not eligible for transplantation has shown significant benefits in progression-free survival and overall survival.

  • 4

    Novel immune and cellular therapies are emerging as potential maintenance options, demonstrating unprecedented efficacy in clinical practice.

  • 5

    A systematic review and network meta-analysis were conducted to compare established and emerging maintenance therapy approaches for treatment selection.

Original Source(s)

The Changing Landscape of Maintenance Therapy in Newly Diagnosed Multiple Myeloma: A Systematic Review With Network Meta-Analysis of the European Myeloma Network (EMN)

  • by Heinz Ludwig, Evangelos Terpos, Francesca Gay, Niels W. C. J. van de Donk, Sarah Bernhard, Monika Engelhardt, Gordon Cook, Fredrik Schjesvold, Hermann Einsele, Graham Jackson, Charlotte Pawlyn, María-Victoria Mateos, Sonja Zweegman, Martin Schreder, Meral Beksaç, Christoph Driessen, Enrique M. Ocio, Rakesh Popat, Leo Rasche, Cyrille Touzeau, Pellegrino Musto, Annemiek Broijl, Meletios Dimopoulos, Roman Hajek, Mario Boccadoro, Pieter Sonneveld

  • June 18, 2026

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