Maternal Intellectual and Developmental Disabilities and Infant Outcomes

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Intellectual and developmental disabilities (IDDs) affect approximately 1% to 2% of the population and include conditions like autism and cerebral palsy.
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Maternal IDDs are associated with significantly worse health outcomes, including a 50% increased risk of preterm birth and small-for-gestational-age births.
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Infants of mothers with IDDs have a 50% to 80% increased risk of NICU admission compared to those born to mothers without disabilities.
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The study utilized a retrospective cohort design, analyzing singleton live birth data from California between 2007 and 2021.
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Maternal IDD subtypes were categorized into five groups, and statistical analyses were conducted to estimate adjusted risk ratios for adverse infant outcomes.

Jama Network Open

by Catherine Psaras, Rita H. Ryu, Rebecca Baer, Kristin Palmsten, Lori Kroh, Jeanne Townsend, Jaime Barea, Jerasimos Ballas, Gretchen Bandoli
May 27, 2026

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