Association of the sdLDL-C/lbLDL-C ratio with heart failure beyond conventional LDL-C levels: a cross-sectional study - Takeaways - MDSpire

Association of the sdLDL-C/lbLDL-C ratio with heart failure beyond conventional LDL-C levels: a cross-sectional study

  • By

  • Xuyang Pan

  • Fang Liu

  • Wei Li

  • Tao Li

  • Changgao Zhou

  • Liting Yang

  • Yanchun Zhang

  • Xingyu Zhu

  • Lina Zheng

  • Yihan Zhou

  • Xue Sun

  • Shushen Ji

  • Yue Wang

  • Jiangman Zhao

  • Guoliang Yuan

  • July 17, 2026

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  • 1

    The study included 584 newly diagnosed heart failure patients and 611 non-heart failure controls to analyze lipid profiles.

  • 2

    Heart failure patients exhibited higher sdLDL-C levels and lower lbLDL-C levels compared to non-heart failure controls.

  • 3

    The sdLDL-C/lbLDL-C ratio was identified as an independent factor associated with heart failure status.

  • 4

    Conventional LDL-C levels did not significantly differ between heart failure patients and controls.

  • 5

    The study highlights the importance of LDL subfraction characteristics in understanding heart failure and cardiac function.

Original Source(s)

Association of the sdLDL-C/lbLDL-C ratio with heart failure beyond conventional LDL-C levels: a cross-sectional study

  • by Xuyang Pan, Fang Liu, Wei Li, Tao Li, Changgao Zhou, Liting Yang, Yanchun Zhang, Xingyu Zhu, Lina Zheng, Yihan Zhou, Xue Sun, Shushen Ji, Yue Wang, Jiangman Zhao, Guoliang Yuan

  • July 17, 2026

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