Dana-Farber Research News 12.15.2025 - Takeaways - MDSpire

Dana-Farber Research News 12.15.2025

This twice-monthly newsletter highlights recently published research where Dana-Farber faculty are listed as first or senior authors. The information is pulled from PubMed and this issue notes papers published from November 16 - 30.

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  • December 15, 2025

  • 19 min

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  • 1

    Dana-Farber's Research News highlights recent publications by faculty, focusing on research from November 16-30, 2025.

  • 2

    Hemophagocytic lymphohistiocytosis (HLH) is a severe condition requiring early recognition and intervention to prevent organ damage and death.

  • 3

    Loss of PTEN promotes tumorigenesis through a mechanism involving PI3K? phosphorylation, creating a target for therapy in PTEN-deficient cancers.

  • 4

    BAX, a pro-apoptotic protein, is inhibited by a dimer of BCL-w, revealing a new layer of apoptotic control through protein interactions.

  • 5

    The PINES trial found that eltrombopag significantly improved platelet response in children with newly diagnosed immune thrombocytopenia.

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Dana-Farber Research News 12.15.2025

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  • December 15, 2025

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