National trends in bone-metastatic prostate cancer mortality in the United States, 1999–2024: a multiple-cause-of-death analysis with projections to 2040 - Takeaways - MDSpire

Trends in Mortality from Bone-Metastatic Prostate Cancer in the U.S. (1999–2024): A Multiple-Cause-of-Death Analysis with Projections Through 2040

  • By

  • Kanza Atif

  • Eshal Atif

  • Vishan Das

  • Alaa Eldeeb

  • Kaneez Fatima

  • Sadia Qazi

  • Aziz Abdullah

  • July 20, 2026

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  • 1

    The study analyzed 25-year trends in prostate cancer mortality with co-documented bone metastasis using CDC WONDER data from 1999 to 2024.

  • 2

    The age-adjusted mortality rate (AAMR) for prostate cancer with bone metastasis increased by 93%, contrasting with a decline in underlying-cause mortality.

  • 3

    Non-Hispanic Black men had a 64% higher mean AAMR compared to non-Hispanic White men, with projections indicating widening disparities by 2040.

  • 4

    Men aged 65-85+ had a 17-fold higher AAMR than those aged 45-64, highlighting significant age-related mortality differences.

  • 5

    The findings suggest the need for incorporating Multiple Cause of Death metrics into national prostate cancer surveillance to address disparities.

Original Source(s)

National trends in bone-metastatic prostate cancer mortality in the United States, 1999–2024: a multiple-cause-of-death analysis with projections to 2040

  • by Kanza Atif, Eshal Atif, Vishan Das, Alaa Eldeeb, Kaneez Fatima, Sadia Qazi, Aziz Abdullah

  • July 20, 2026

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