One-year breakthrough SARS-CoV-2 infection and correlates of protection in fully vaccinated hematological patients

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Hematological patients are at high risk for severe COVID-19, with early pandemic mortality rates exceeding 25%.
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Vaccination has significantly reduced mortality in these patients, dropping to less than 10% during 2022.
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Breakthrough infections remain common in vaccinated hematological patients, with high hospitalization and ICU admission rates.
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The study analyzed 1551 fully vaccinated hematological patients to assess breakthrough infection incidence and severity.
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Serological assessments showed a high rate of missing data over time, impacting the analysis of breakthrough infection risks.

Blood Cancer Journal

by José Luis Piñana, Lourdes Vazquez, Marisa Calabuig, Lucia López-Corral, Gabriel Martin-Martin, Lucia Villalon, Gabriela Sanz-Linares, Venancio Conesa-Garcia, Andrés Sanchez-Salinas, Beatriz Gago, Ana Facal, Irene Risco-Gálvez, María T. Olave, Ildefonso Espigado, Javier Lopez-Jimenez, José Ángel Hernández-Rivas, Alejandro Avendaño-Pita, Ignacio Arroyo, Elena Ferrer, Irene García-Cadenas, Clara González-Santillana, Alicia Roldán-Pérez, Blanca Ferrer, Manuel Guerreiro, María Suarez-Lledó, Angela Camara, Diana Campos-Beltrán, David Navarro, Ángel Cedillo, Anna Sureda, Carlos Solano, Rodrigo Martino
January 5, 2023

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