When Constipation Signals Something More
Coordinated clinical and public health response supports timely identification and recovery of infant botulism.
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By
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Kathryn Wighton
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February 9, 2026
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1
A previously healthy infant developed constipation, feeding difficulties, and progressive flaccid paralysis, requiring intensive care.
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Initial tests for infection and structural abnormalities were negative, prompting further investigation for botulism.
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Nerve conduction studies indicated infant botulism, leading to the administration of equine-derived antitoxin.
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Laboratory confirmation of Clostridium botulinum type B occurred on day 7, and the infant received Botulism Immune Globulin.
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The case highlights the importance of rapid recognition, investigation, and public health coordination in managing infant botulism.