When Constipation Signals Something More - Takeaways - MDSpire

When Constipation Signals Something More

  • By

  • Kathryn Wighton

  • February 9, 2026

  • 2 min

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  • 1

    A previously healthy infant developed constipation, feeding difficulties, and progressive flaccid paralysis, requiring intensive care.

  • 2

    Initial tests for infection and structural abnormalities were negative, prompting further investigation for botulism.

  • 3

    Nerve conduction studies indicated infant botulism, leading to the administration of equine-derived antitoxin.

  • 4

    Laboratory confirmation of Clostridium botulinum type B occurred on day 7, and the infant received Botulism Immune Globulin.

  • 5

    The case highlights the importance of rapid recognition, investigation, and public health coordination in managing infant botulism.

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