Joint effects of severe obesity and inflammation on mortality in critically ill non−ST−segment elevation myocardial infarction patients: a cohort study with external validation - Takeaways - MDSpire

Joint effects of severe obesity and inflammation on mortality in critically ill non−ST−segment elevation myocardial infarction patients: a cohort study with external validation

  • By

  • Yuqing Li

  • Yuhang Wang

  • Pengju Lu

  • Jiaxin Wang

  • Weiwei Tian

  • Ran Chu

  • Jingxi Chen

  • Lai Jiang

  • Changping Li

  • Yin Liu

  • Jing Gao

  • June 24, 2026

  • 0 min

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  • 1

    The study analyzed 7,815 critically ill NSTEMI patients to assess the impact of BMI and CRP on mortality.

  • 2

    Severe obesity (BMI ≥ 35 kg/m2) was linked to higher in-hospital and 10-year all-cause mortality in NSTEMI patients.

  • 3

    Overweight and obesity I categories showed lower mortality risk compared to normal weight individuals.

  • 4

    The combination of severe obesity and elevated CRP identified a high-risk clinical profile without significant interaction.

  • 5

    Adding CRP to the risk model improved mortality prediction metrics, indicating its value in risk stratification.

Original Source(s)

Joint effects of severe obesity and inflammation on mortality in critically ill non−ST−segment elevation myocardial infarction patients: a cohort study with external validation

  • by Yuqing Li, Yuhang Wang, Pengju Lu, Jiaxin Wang, Weiwei Tian, Ran Chu, Jingxi Chen, Lai Jiang, Changping Li, Yin Liu, Jing Gao

  • June 24, 2026

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