Immunologically-based nutritional status assessment amongst preoperative colorectal cancer patients – does it link to TNM stage - Takeaways - MDSpire

Immunologically-based nutritional status assessment amongst preoperative colorectal cancer patients – does it link to TNM stage

  • By

  • Karolina Kaźmierczak-Siedlecka

  • Piotr Wiśniewski

  • Robert Kucharski

  • Ewa Stachowska

  • Wojciech Makarewicz

  • July 10, 2026

  • 0 min

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  • 1

    Disease-related malnutrition in colorectal cancer patients negatively impacts postoperative clinical outcomes.

  • 2

    The study analyzed immunonutritional status in preoperative colorectal cancer patients using albumin-to-globulin ratio and prognostic nutritional index.

  • 3

    Among 12 selected patients, 67% were classified as T3, with 50% showing lymph node metastasis and no distant metastases.

  • 4

    The optimal cut-off value for prognostic nutritional index was determined to be 51.74, dividing patients into PNI-low and PNI-high groups.

  • 5

    Lymph node metastasis was more frequently observed in the PNI-high group, suggesting a potential link between PNI and local disease progression.

Original Source(s)

Immunologically-based nutritional status assessment amongst preoperative colorectal cancer patients – does it link to TNM stage

  • by Karolina Kaźmierczak-Siedlecka, Piotr Wiśniewski, Robert Kucharski, Ewa Stachowska, Wojciech Makarewicz

  • July 10, 2026

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