Marked Increase in Diabetic Ketoacidosis Rates With Modest Increase in HbA1c Elevation at Diabetes Diagnosis in Swedish Children - Takeaways - MDSpire
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Significant Rise in Diabetic Ketoacidosis Incidence Linked to Slight Increase in HbA1c Levels at Type 1 Diabetes Diagnosis Among Swedish Pediatric Patients

  • By

  • Frida Sundberg

  • Katarina Eeg-Olofsson

  • Karin Åkesson

  • September 17, 2026

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  • 1

    The incidence of diabetic ketoacidosis (DKA) at type 1 diabetes diagnosis among Swedish children has increased to 30% in 2025.

  • 2

    During 2007-2011, severe DKA occurred in 4.3%-8.6% of newly diagnosed children, rising to 8.4%-10% in 2021-2025.

  • 3

    Mean HbA1c levels at diagnosis increased slightly from 92-97 mmol/mol (2007-2011) to 96-98 mmol/mol (2021-2025).

  • 4

    The rise in DKA incidence may indicate a more aggressive disease progression rather than solely delayed diagnosis.

  • 5

    Data from the Swediabkids/National Diabetes Register requires thorough evaluation to understand the relationship between HbA1c and age.

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