International Variations in Glioblastoma Management: A Comprehensive Review - Takeaways - MDSpire

International Variations in Glioblastoma Management: A Comprehensive Review

  • By

  • Reuben Christopher

  • Livia Stauner

  • Mathias Spendel

  • Arwin Rezai

  • Alexander Romagna

  • Christoph Schwartz

  • March 27, 2026

  • 0 min

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  • 1

    Glioblastoma (GBM) is the most aggressive primary brain tumor in adults, with a median survival of 15–17 months post-diagnosis.

  • 2

    The Stupp protocol, which includes surgical resection and temozolomide chemotherapy, is the current standard of care for GBM.

  • 3

    Despite advancements, over 50% of GBM patients experience tumor recurrence within seven months of initial treatment.

  • 4

    Economic evaluations of GBM treatments reveal significant global variations in costs and cost-effectiveness of modern therapies.

  • 5

    This systematic review aims to quantify the economic differences in GBM care, focusing on costs and treatment effectiveness since 2005.

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