Clinical Insights: A Reversible Autonomic-Endothelial Migraine Phenomenon Demonstrated Through a Case Study - Takeaways - MDSpire

Clinical Insights: A Reversible Autonomic-Endothelial Migraine Phenomenon Demonstrated Through a Case Study

  • By

  • Vlodeks Gromakovskis

  • April 14, 2026

  • 0 min

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  • 1

    A 41-year-old male with a 10-year history of migraine without aura experienced sustained remission after starting antihypertensive therapy.

  • 2

    The patient's migraines were triggered by strong odors and accompanied by cranial-autonomic symptoms like nasal congestion and sneezing.

  • 3

    Combined antihypertensive therapy normalized blood pressure and resolved migraine and nasal symptoms within two weeks.

  • 4

    Remission of migraine symptoms persisted for 12 months, indicating a potential link between vascular homeostasis and migraine management.

  • 5

    This case suggests that endothelial and autonomic factors may play a role in migraine chronification and remission.

Original Source(s)

Clinical Insights: A Reversible Autonomic-Endothelial Migraine Phenomenon Demonstrated Through a Case Study

  • by Vlodeks Gromakovskis

  • April 14, 2026

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