Association between endogenous oxytocin levels and live birth rates following fresh embryo transfer: a prospective cohort study - Takeaways - MDSpire

Association between endogenous oxytocin levels and live birth rates following fresh embryo transfer: a prospective cohort study

  • By

  • Ruiqiong Zhou

  • Zhaoyi Wang

  • Zhenghong Zhu

  • Mei Dong

  • Jiao Wang

  • Li Huang

  • Quan Qi

  • Xiqian Zhang

  • Fenghua Liu

  • June 2, 2026

  • 0 min

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  • 1

    This study analyzed the relationship between endogenous oxytocin levels and live birth rates in IVF cycles.

  • 2

    Higher serum oxytocin levels were negatively associated with live birth rates, decreasing the likelihood by 37% per 100 pg/mL increase.

  • 3

    In contrast, elevated follicular fluid oxytocin levels positively correlated with live birth rates, improving the likelihood by 18% per 100 pg/mL increase.

  • 4

    Serum oxytocin levels correlated positively with triglycerides, LDL-C, and insulin, but negatively with HDL-C.

  • 5

    Follicular fluid oxytocin levels correlated positively with ovarian response markers, including estradiol and oocytes retrieved.

Original Source(s)

Association between endogenous oxytocin levels and live birth rates following fresh embryo transfer: a prospective cohort study

  • by Ruiqiong Zhou, Zhaoyi Wang, Zhenghong Zhu, Mei Dong, Jiao Wang, Li Huang, Quan Qi, Xiqian Zhang, Fenghua Liu

  • June 2, 2026

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