Glycemic variability and the short-term mortality of hospitalized patients with COVID-19: a meta-analysis - Takeaways - MDSpire

Glycemic variability and the short-term mortality of hospitalized patients with COVID-19: a meta-analysis

  • By

  • Zixuan Wang

  • Jingyi Wang

  • Qiao Wu

  • Baozeng Wang

  • June 16, 2026

  • 0 min

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  • 1

    High glycemic variability (GV) is significantly associated with increased short-term mortality in hospitalized COVID-19 patients.

  • 2

    The meta-analysis included 10 cohort studies with 77,395 patients, revealing 8,189 deaths linked to high GV.

  • 3

    The risk ratio for mortality associated with high GV was 2.10, indicating more than double the risk compared to low GV.

  • 4

    Older patients (mean age ≥ 62 years) showed a stronger association between high GV and mortality (RR = 2.79) than younger patients.

  • 5

    The findings support the potential of GV as a prognostic marker for short-term mortality in COVID-19 hospitalized patients.

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