Clinical profile of headache attributed to anxiety and depressive disorders: an observational study - Takeaways - MDSpire

Clinical profile of headache attributed to anxiety and depressive disorders: an observational study

  • By

  • Boyan Chen

  • Sailucao Zhang

  • Jing Yang

  • Xinyu Yan

  • Chunyu Wang

  • Dongjun Wan

  • May 18, 2026

  • 0 min

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  • 1

    The study enrolled 101 patients with headache attributed to anxiety and depressive disorders (HA-ADD) at a headache center in China.

  • 2

    The cohort was predominantly female (70.3%) with a median age of 36 years, highlighting demographic trends in HA-ADD.

  • 3

    Characteristic HA-ADD features included bilateral, dull pain of moderate-to-severe intensity, with 60.4% of attacks lasting less than 4 hours.

  • 4

    Associated symptoms of HA-ADD included phonophobia (79.2%), restlessness/agitation (58.4%), and dizziness (57.4%), indicating significant functional impairment.

  • 5

    The findings provide clinical markers that may facilitate earlier diagnosis and appropriate therapeutic intervention for HA-ADD.

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