Efficacy Assessment of Intradermal Stromal Vascular Fraction Injection Compared to Saline Injection for Treating Atrophic Acne Scars: A 10-Week, Prospective, Randomized, Split-Face, Single-Blind Study - Takeaways - MDSpire
Coming Soon: Introducing MDSpire News. Learn more
Conexiant’s news site is now MDSpire News. Learn more

Efficacy Assessment of Intradermal Stromal Vascular Fraction Injection Compared to Saline Injection for Treating Atrophic Acne Scars: A 10-Week, Prospective, Randomized, Split-Face, Single-Blind Study

  • By

  • Joong Heon Suh

  • Ji-Young Kim

  • Ji Young Yoon

  • Jun Hyo Lee

  • Dong Hyo Kim

  • Ungsik Jin

  • Dae Hun Suh

  • December 18, 2025

Share

  • 1

    Intradermal stromal vascular fraction (SVF) injection significantly improved atrophic acne scars compared to saline injection in a randomized clinical trial.

  • 2

    The study demonstrated that SVF reduced scar counts and improved clinical assessment scores for atrophic acne scars.

  • 3

    SVF treatment enhanced epidermal progenitor activity and promoted dermal matrix remodeling, indicating its regenerative potential.

  • 4

    The trial involved 14 participants with bilateral atrophic acne scars, ensuring a controlled comparison between SVF and saline.

  • 5

    This research highlights the need for further investigation into SVF as a standalone treatment for atrophic acne scars.

Original Source(s)

Efficacy Assessment of Intradermal Stromal Vascular Fraction Injection Compared to Saline Injection for Treating Atrophic Acne Scars: A 10-Week, Prospective, Randomized, Split-Face, Single-Blind Study

  • by Joong Heon Suh, Ji-Young Kim, Ji Young Yoon, Jun Hyo Lee, Dong Hyo Kim, Ungsik Jin, Dae Hun Suh

  • December 18, 2025

Related Content

Top 10 Evidence-Based Essentials in Dermatology

A structured framework of guidelines, trials, therapies, and tools used in clinical practice

Papulopustular eruptions associated with EGFR-pathway-related targeted therapies: clinical spectrum, evidence boundaries, folliculocentric inflammation, and management considerations

More States Fast Track Foreign-Trained Physicians

Since 2023, nine states have waived U.S. residency requirements for some foreign-trained physicians, with more states considering similar changes.