Efficacy Assessment of Intradermal Stromal Vascular Fraction Injection Compared to Saline Injection for Treating Atrophic Acne Scars: A 10-Week, Prospective, Randomized, Split-Face, Single-Blind Study - Takeaways - MDSpire

Efficacy Assessment of Intradermal Stromal Vascular Fraction Injection Compared to Saline Injection for Treating Atrophic Acne Scars: A 10-Week, Prospective, Randomized, Split-Face, Single-Blind Study

  • By

  • Joong Heon Suh

  • Ji-Young Kim

  • Ji Young Yoon

  • Jun Hyo Lee

  • Dong Hyo Kim

  • Ungsik Jin

  • Dae Hun Suh

  • December 18, 2025

  • 0 min

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  • 1

    Intradermal stromal vascular fraction (SVF) injection significantly improved atrophic acne scars compared to saline injection in a randomized clinical trial.

  • 2

    The study demonstrated that SVF reduced scar counts and improved clinical assessment scores for atrophic acne scars.

  • 3

    SVF treatment enhanced epidermal progenitor activity and promoted dermal matrix remodeling, indicating its regenerative potential.

  • 4

    The trial involved 14 participants with bilateral atrophic acne scars, ensuring a controlled comparison between SVF and saline.

  • 5

    This research highlights the need for further investigation into SVF as a standalone treatment for atrophic acne scars.

Original Source(s)

Efficacy Assessment of Intradermal Stromal Vascular Fraction Injection Compared to Saline Injection for Treating Atrophic Acne Scars: A 10-Week, Prospective, Randomized, Split-Face, Single-Blind Study

  • by Joong Heon Suh, Ji-Young Kim, Ji Young Yoon, Jun Hyo Lee, Dong Hyo Kim, Ungsik Jin, Dae Hun Suh

  • December 18, 2025

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