Preterm birth and the association with neurodevelopmental disorders (NDDs) in children born in Pakistan: a retrospective cross-sectional study - Takeaways - MDSpire

Linking Preterm Birth to Neurodevelopmental Disorders in Pakistani Children: Findings from a Retrospective Cross-Sectional Analysis

  • By

  • Arsalan Tariq

  • Abdul Saad

  • July 20, 2026

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  • 1

    The study analyzed medical records of 2634 Pakistani children aged 2–6 years to assess the link between preterm birth and neurodevelopmental disorders.

  • 2

    Preterm birth prevalence was 27.7%, with neurodevelopmental disorder rates significantly higher in preterm children compared to full-term children.

  • 3

    The prevalence of neurodevelopmental disorders increased with the severity of prematurity, reaching 55.6% in extremely preterm children.

  • 4

    Multivariable analysis identified preterm birth, low maternal education, male sex, low income, and NICU admission as independent risk factors for neurodevelopmental disorders.

  • 5

    Children who were preterm and from low socioeconomic status households had the highest odds of neurodevelopmental disorders, with an adjusted odds ratio of 9.43.

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