Early arterial blood gas parameters, clinical features, and neuroimaging findings in neonates undergoing therapeutic hypothermia for suspected hypoxic-ischemic encephalopathy: a retrospective single-center study - Takeaways - MDSpire

Early arterial blood gas parameters, clinical features, and neuroimaging findings in neonates undergoing therapeutic hypothermia for suspected hypoxic-ischemic encephalopathy: a retrospective single-center study

  • By

  • Ece Gültekin

  • July 9, 2026

  • 0 min

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  • 1

    The study analyzed 22 neonates treated with therapeutic hypothermia for suspected hypoxic-ischemic encephalopathy (HIE).

  • 2

    Final HIE classification revealed no evidence of HIE in 72.7% of patients, with varying stages of HIE in the remainder.

  • 3

    Lower bicarbonate levels were significantly associated with the presence of any-stage HIE compared to neonates without HIE.

  • 4

    Neonates with seizures had lower gestational age and more negative base excess values, indicating more severe metabolic acidosis.

  • 5

    The study found low concordance between cranial ultrasonography and MRI, with many neonates having abnormal MRI despite normal ultrasonography.

Original Source(s)

Early arterial blood gas parameters, clinical features, and neuroimaging findings in neonates undergoing therapeutic hypothermia for suspected hypoxic-ischemic encephalopathy: a retrospective single-center study

  • by Ece Gültekin

  • July 9, 2026

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