Exploratory EEG correlates of sensory and affective pain dimensions in patients with chronic widespread pain - Takeaways - MDSpire

Exploratory EEG correlates of sensory and affective pain dimensions in patients with chronic widespread pain

  • By

  • Keita Ueno

  • Keiko Yamada

  • Masaya Ueda

  • Yasuo Naito

  • Ryouhei Ishii

  • July 16, 2026

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  • 1

    This study explored neurophysiological correlations of sensory and affective pain dimensions in chronic widespread pain using resting-state EEG data.

  • 2

    Data from 20 chronic widespread pain patients and 22 healthy controls were analyzed for current source density and functional connectivity.

  • 3

    Current pain intensity in CWP patients was negatively correlated with CSD values in the γ bands of the precuneus/posterior cingulate cortex.

  • 4

    The affective pain component showed a positive correlation with δ band functional connectivity between the anterior cingulate cortex and right anterior insula.

  • 5

    The findings suggest potential neurophysiological insights into chronic widespread pain, warranting further research with larger samples.

Original Source(s)

Exploratory EEG correlates of sensory and affective pain dimensions in patients with chronic widespread pain

  • by Keita Ueno, Keiko Yamada, Masaya Ueda, Yasuo Naito, Ryouhei Ishii

  • July 16, 2026

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