Neurophysiological Associations of Sensory and Emotional Pain Aspects in Individuals with Chronic Widespread Pain: An EEG Exploration

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This study explored neurophysiological correlations of sensory and affective pain dimensions in chronic widespread pain using resting-state EEG data.
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Data from 20 chronic widespread pain patients and 22 healthy controls were analyzed for current source density and functional connectivity.
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Current pain intensity in CWP patients was negatively correlated with CSD values in the γ bands of the precuneus/posterior cingulate cortex.
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The affective pain component showed a positive correlation with δ band functional connectivity between the anterior cingulate cortex and right anterior insula.
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The findings suggest potential neurophysiological insights into chronic widespread pain, warranting further research with larger samples.

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