Efficacy and Safety of Bimekizumab in Psoriatic Arthritis Patients with Significant Skin and Nail Involvement Over One Year - Takeaways - MDSpire
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Efficacy and Safety of Bimekizumab in Psoriatic Arthritis Patients with Significant Skin and Nail Involvement Over One Year

  • By

  • Diamant Thaçi

  • Akihiko Asahina

  • Wolf-Henning Boehncke

  • Alice B. Gottlieb

  • Mark Lebwohl

  • Richard B. Warren

  • Heather Edens

  • Barbara Ink

  • Rajan Bajracharya

  • Jason Coarse

  • Joseph F. Merola

  • December 12, 2025

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  • 1

    Bimekizumab significantly improved disease symptoms in PsA patients with skin and nail involvement compared to placebo at week 16.

  • 2

    Improvements in disease domains with bimekizumab were sustained through week 52 for both biologic-naïve and TNFi-IR patients.

  • 3

    The treatment was well tolerated, with no new safety concerns identified during the study.

  • 4

    Bimekizumab's efficacy in treating PsA with concomitant plaque-type psoriasis and nail involvement is clinically relevant.

  • 5

    This study provides valuable data for clinicians in selecting effective treatments for patients with severe PsA symptoms.

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