Internet Searches for Leucovorin, Folate, and Acetaminophen After a White House Autism Announcement

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The White House announcement on September 22, 2025, endorsed leucovorin for autism treatment and warned against acetaminophen use during pregnancy.
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Following the announcement, searches for leucovorin increased by 378.7% and for folinic acid or folate by 53.2%, indicating heightened public interest.
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Acetaminophen searches rose by 186.8%, with a staggering 1322.4% increase in searches combining acetaminophen with autism or pregnancy.
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The study highlighted that political announcements can significantly influence health behaviors and consumer interest in medical products.
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Findings suggest that health leaders should be cautious about endorsing medical products based on limited evidence due to potential public impact.

Jama Network Open

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