The Effectiveness and Safety of Romosozumab and Teriparatide in Postmenopausal Women With Osteoporosis - Takeaways - MDSpire

The Effectiveness and Safety of Romosozumab and Teriparatide in Postmenopausal Women With Osteoporosis

  • By

  • Martin C Hartz

  • Fabian B Johannessen

  • Torben Harsløf

  • Bente L Langdahl

  • July 16, 2024

  • 0 min

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  • 1

    Romosozumab (ROMO) significantly increases bone mineral density (BMD) more than teriparatide (TPTD) in postmenopausal women after 12 months.

  • 2

    The study included 315 postmenopausal women meeting specific criteria for ROMO and TPTD treatment at Aarhus University Hospital.

  • 3

    ROMO demonstrated a lower discontinuation rate and fewer cardiovascular adverse events compared to TPTD.

  • 4

    Treatment-naïve patients showed nonsignificantly higher BMD increases with both ROMO and TPTD compared to previously treated patients.

  • 5

    Both ROMO and TPTD are generally safe, but ROMO is contraindicated in patients with a history of myocardial infarction or stroke.

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