Clinical Guidelines Feature Innovative, Minimally Invasive Treatment for Drug-Resistant Epilepsy Epilepsy remains a life-altering condition, particularly due to the unpredictable nature of seizures and their cumulative impact on cognition, independence and quality of life. May 8, 2026 5 min Phoenix Children's Medical Connection Share Summary Takeaways 1 Epilepsy can severely affect independence and quality of life. 2 One-third of epilepsy patients experience drug-resistant epilepsy. 3 sEEG and RF-TC can provide effective treatments. 4 A multidisciplinary team is essential for complex cases. 5 Early referral to a Level 4 epilepsy center is critical for optimal outcomes. 6 New treatments are emerging to improve care for complex epilepsy. 7 Close collaboration among specialists enhances treatment strategies. 8 Phoenix Children's Epilepsy Program offers advanced care options.