Venous thromboembolism in adolescents and young adults with acute lymphoblastic leukemia treated on a pediatric-inspired regimen - Takeaways - MDSpire

Venous thromboembolism in adolescents and young adults with acute lymphoblastic leukemia treated on a pediatric-inspired regimen

  • By

  • Shai Shimony

  • Hari S. Raman

  • Yael Flamand

  • Julia Keating

  • Jonathan D. Paolino

  • Yannis K. Valtis

  • Andrew E. Place

  • Lewis B. Silverman

  • Stephen E. Sallan

  • Lynda M. Vrooman

  • Andrew M. Brunner

  • Donna S. Neuberg

  • Ilene Galinsky

  • Jacqueline S. Garcia

  • Eric S. Winer

  • Martha Wadleigh

  • Richard M. Stone

  • Jean M. Connors

  • Daniel J. DeAngelo

  • Marlise R. Luskin

  • October 31, 2024

  • 0 min

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  • 1

    Adolescent and young adult patients with acute lymphoblastic leukemia may experience a 5% to 34% incidence of venous thromboembolism when treated with asparaginase.

  • 2

    Asparaginase treatment is associated with increased risk for venous thromboembolism due to decreased synthesis of anticoagulant proteins.

  • 3

    A retrospective study included 341 patients, revealing that 33.4% experienced at least one venous thromboembolism event during treatment.

  • 4

    Higher body mass index was associated with increased rates of venous thromboembolism in patients with acute lymphoblastic leukemia.

  • 5

    The study aimed to evaluate the prevalence, risk factors, and clinical impact of venous thromboembolism in adolescents and young adults with ALL.

Original Source(s)

Venous thromboembolism in adolescents and young adults with acute lymphoblastic leukemia treated on a pediatric-inspired regimen

  • by Shai Shimony, Hari S. Raman, Yael Flamand, Julia Keating, Jonathan D. Paolino, Yannis K. Valtis, Andrew E. Place, Lewis B. Silverman, Stephen E. Sallan, Lynda M. Vrooman, Andrew M. Brunner, Donna S. Neuberg, Ilene Galinsky, Jacqueline S. Garcia, Eric S. Winer, Martha Wadleigh, Richard M. Stone, Jean M. Connors, Daniel J. DeAngelo, Marlise R. Luskin

  • October 31, 2024

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