Effect of bariatric surgery on matrix metalloproteinase activity in patients with morbid obesity - Takeaways - MDSpire

Effect of bariatric surgery on matrix metalloproteinase activity in patients with morbid obesity

  • By

  • Barbara Choromańska

  • Piotr Myśliwiec

  • Jacek Dadan

  • Alan Tkaczuk

  • Konrad Wiśniewski

  • Almantas Maleckas

  • Anna Zalewska

  • Małgorzata Żendzian-Piotrowska

  • Mateusz Maciejczyk

  • June 15, 2026

  • 0 min

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  • 1

    The study evaluated plasma activity of matrix metalloproteinases (MMPs) in women with morbid obesity before and after laparoscopic sleeve gastrectomy.

  • 2

    Increased plasma activities of various MMPs were observed in morbidly obese women, particularly those with metabolic syndrome.

  • 3

    Post-surgery, only some plasma MMP activities partially normalized, indicating persistent disturbances in MMP homeostasis.

  • 4

    The research involved 63 women with class 3 obesity, categorized into groups based on the presence of metabolic syndrome.

  • 5

    Further long-term studies are needed to validate the findings regarding MMP activity and its implications in obesity.

Original Source(s)

Effect of bariatric surgery on matrix metalloproteinase activity in patients with morbid obesity

  • by Barbara Choromańska, Piotr Myśliwiec, Jacek Dadan, Alan Tkaczuk, Konrad Wiśniewski, Almantas Maleckas, Anna Zalewska, Małgorzata Żendzian-Piotrowska, Mateusz Maciejczyk

  • June 15, 2026

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