Preoperative radioembolization versus chemoembolization and upfront resection for resectable hepatocellular carcinoma beyond the Milan criteria - Takeaways - MDSpire
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Preoperative Radioembolization Compared with Chemoembolization or Immediate Resection for Resectable Hepatocellular Carcinoma Outside the Milan Criteria

  • By

  • Jeayeon Park

  • Gyung Sun Lim

  • Yunmi Ko

  • Hyunjae Shin

  • Moon Haeng Hur

  • Su Young Hong

  • Suk Kyun Hong

  • Yun Bin Lee

  • Eun Ju Cho

  • Jeong-Hoon Lee

  • YoungRok Choi

  • Su Jong Yu

  • Hyo-Cheol Kim

  • Kwang-Woong Lee

  • Jung-Hwan Yoon

  • Kyung-Suk Suh

  • Jin Wook Chung

  • Yoon Jun Kim

  • October 7, 2026

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  • 1

    The study evaluated preoperative TARE and TACE versus immediate resection for technically resectable HCC beyond the Milan criteria.

  • 2

    The retrospective cohort included consecutive patients treated at Seoul National University Hospital from January 2016 through July 2024.

  • 3

    Eligible patients had Child-Pugh class A liver function, ECOG performance status 0 or 1, acceptable operative risk, and adequate future liver remnant.

  • 4

    A multidisciplinary tumor board selected preoperative TARE, preoperative TACE, or primary resection based on tumor burden, liver function, resectability, and physician discretion.

  • 5

    Because all patients were resectable at baseline and underwent resection, preoperative TARE and TACE were classified as neoadjuvant therapies, not downstaging or transplant-bridging treatments.

Original Source(s)

Preoperative radioembolization versus chemoembolization and upfront resection for resectable hepatocellular carcinoma beyond the Milan criteria

  • by Jeayeon Park, Gyung Sun Lim, Yunmi Ko, Hyunjae Shin, Moon Haeng Hur, Su Young Hong, Suk Kyun Hong, Yun Bin Lee, Eun Ju Cho, Jeong-Hoon Lee, YoungRok Choi, Su Jong Yu, Hyo-Cheol Kim, Kwang-Woong Lee, Jung-Hwan Yoon, Kyung-Suk Suh, Jin Wook Chung, Yoon Jun Kim

  • October 7, 2026

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