Comparative predictive performance of different eGFR equations for 1-year major adverse cardiovascular events after percutaneous coronary intervention in patients with acute coronary syndrome - Takeaways - MDSpire
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Evaluation of Various eGFR Formulas in Predicting 1-Year Major Adverse Cardiovascular Events Following Percutaneous Coronary Intervention in Acute Coronary Syndrome Patients

  • By

  • Yicheng Wang

  • Fangming Liu

  • Ruoxi Qi

  • Xiaohan Wang

  • Jiajie Mei

  • Zhenzhu Liu

  • Lijiao Zhang

  • Wenli Xie

  • Ming Yu

  • Xiaodong Zhang

  • Hongyan Wang

  • Zhaohong Geng

  • September 9, 2026

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  • 1

    The study evaluated the predictive performance of creatinine-based versus cystatin C–based eGFR equations for 1-year MACE in PCI patients.

  • 2

    A cohort of 560 patients undergoing PCI for acute coronary syndrome was analyzed, with 72 experiencing MACE during the follow-up.

  • 3

    Cystatin C–based equations identified more patients with impaired renal function compared to creatinine-based formulas.

  • 4

    Logistic regression showed the greatest discriminative ability for predicting 1-year MACE, while machine learning models had modest performance.

  • 5

    Creatinine-based eGFR was more strongly associated with 1-year MACE than cystatin C–based eGFR, but neither showed clinical superiority.

Original Source(s)

Comparative predictive performance of different eGFR equations for 1-year major adverse cardiovascular events after percutaneous coronary intervention in patients with acute coronary syndrome

  • by Yicheng Wang, Fangming Liu, Ruoxi Qi, Xiaohan Wang, Jiajie Mei, Zhenzhu Liu, Lijiao Zhang, Wenli Xie, Ming Yu, Xiaodong Zhang, Hongyan Wang, Zhaohong Geng

  • September 9, 2026

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